diff --git a/chrome/browser/ui/webui/whats_new/whats_new_util.cc b/chrome/browser/ui/webui/whats_new/whats_new_util.cc
index 8b12affd2b97b..93389bc56ba53 100644
--- a/chrome/browser/ui/webui/whats_new/whats_new_util.cc
+++ b/chrome/browser/ui/webui/whats_new/whats_new_util.cc
@@ -33,12 +33,14 @@ BASE_FEATURE(kForceEnabled,
 #endif
 
 bool IsEnabled() {
-#if BUILDFLAG(GOOGLE_CHROME_BRANDING) && !BUILDFLAG(IS_CHROMEOS)
+#if BUILDFLAG(IS_CHROMEOS)
+  return false;
+#elif BUILDFLAG(GOOGLE_CHROME_BRANDING) || defined(ADDRESS_SANITIZER)
+  // Keep chrome://whats-new/ available in ASan builds without requiring
+  // Chrome branding or feature-list overrides.
   return true;
-#elif !BUILDFLAG(IS_CHROMEOS)
-  return base::FeatureList::IsEnabled(whats_new::kForceEnabled);
 #else
-  return false;
+  return base::FeatureList::IsEnabled(whats_new::kForceEnabled);
 #endif
 }